When we think of oxytocin, the image of a warm embrace or the deep connection between a mother and her child often comes to mind. 



This hormone, often dubbed the "love hormone" or "cuddle hormone," is famous for its role in fostering emotional bonds and promoting feelings of trust and empathy. 



But recent studies suggest that oxytocin might be doing much more behind the scenes, especially when it comes to how we learn and remember. And more surprisingly, it may also help cure addiction.



Leading this exciting exploration are Professor Akiyoshi Saitoh and researcher Junpei Takahashi from the <a href="https://www.tus.ac.jp/en/" target="_blank" rel="noreferrer noopener">Tokyo University of Science</a>, and Meredith Berry, Ph.D. from the <a href="http://www.ufl.edu/" target="_blank" rel="noreferrer noopener">University of Florida</a>. 



They have been delving into the intricate ways oxytocin influences our brains, potentially paving the way for new treatments for conditions like dementia and <a href="https://www.earth.com/news/brain-discovery-offers-hope-for-tackling-opioid-addiction/" target="_blank" rel="noreferrer noopener">opioid addiction</a>.



<h2 class="wp-block-heading" id="h-oxytocin-s-role-in-memory">Oxytocin's role in memory</h2>



While oxytocin is well-known for its impact on social behaviors, its role in cognitive functions is less understood. 



Professor Saitoh's team wanted to uncover whether oxytocin could be a key player in <a href="https://www.earth.com/news/how-does-our-brain-form-long-term-memories/" target="_blank" rel="noreferrer noopener">how memories are formed</a> and retained. 



“Previously we had suggested that oxytocin may be a new therapeutic candidate for dementia based on studies using a mouse model of <a href="https://www.earth.com/news/alzheimers-disease-attacks-the-brain-in-two-separate-phases/" target="_blank" rel="noreferrer noopener">Alzheimer’s disease</a>,” he shared. 



“To investigate this further, in this study, we examined the role of endogenous oxytocin in mouse cognitive function.”



Using advanced techniques, the researchers specifically activated oxytocin neurons in certain brain regions of mice. 



They then evaluated the mice's memory using tasks designed to test recognition and recall, like the <a href="https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/novel-object-recognition-test" target="_blank" rel="noreferrer noopener">Novel Object Recognition Task</a>. 



This method helps scientists determine how well an animal can recognize a new object compared to one they've seen before.



<h2 class="wp-block-heading" id="h-peering-into-the-brain-s-memory-centers">Peering into the brain's memory centers</h2>



The brain is a complex network, and understanding how different areas interact is crucial. 



The team noticed that when they stimulated oxytocin neurons in the paraventricular hypothalamic nucleus (PVN), there was increased activity not only there but also in the supramammillary nucleus (SuM). 



These regions are connected and play roles in memory and <a href="https://www.earth.com/news/music-causes-similar-emotional-experiences-and-sensations-in-all-cultures/" target="_blank" rel="noreferrer noopener">emotional responses</a>.



By observing markers that indicate neuron activation, they confirmed that these areas were more active following their interventions. 



Interestingly, while the mice didn't show significant changes in short-term memory tasks, there was a noticeable improvement in long-term memory, particularly in recognizing new objects.



<h2 class="wp-block-heading" id="h-oxytocin-connection-to-dementia">Oxytocin connection to dementia</h2>



These findings have significant implications. <a href="https://www.earth.com/news/herbal-medicine-shows-potential-to-treat-and-prevent-dementia/" target="_blank" rel="noreferrer noopener">Dementia</a>, including Alzheimer's disease, affects millions worldwide, leading to memory loss and cognitive decline. 



Understanding how oxytocin influences memory could lead to new therapies that slow down or mitigate these effects.



There's also a broader social context. Many believe that loneliness and lack of social interaction can worsen <a href="https://www.earth.com/news/dementia-was-extremely-rare-in-ancient-times-so-why-is-it-now-so-prevalent/" target="_blank" rel="noreferrer noopener">dementia symptoms</a>. 



“There is a widely acknowledged belief that dementia tends to advance more rapidly in settings where individuals experience loneliness or limited social engagement. However, the scientific underpinnings of this phenomenon have remained largely elusive," Professor Saitoh pointed out.



By highlighting oxytocin's role, the research suggests that stimulating social interactions -- or even directly targeting oxytocin pathways -- might help in <a href="https://www.earth.com/news/diabetes-drugs-may-protect-against-dementia/" target="_blank" rel="noreferrer noopener">managing dementia</a>.



<h2 class="wp-block-heading" id="h-oxytocin-and-opioid-addiction">Oxytocin and opioid addiction</h2>



Across the globe, another team is exploring oxytocin's potential in a different arena. 



At the University of Florida, researchers are investigating whether a synthetic version of oxytocin can help curb opioid addictions, a pressing issue affecting many communities.



“The idea is that physicians could potentially prescribe, in combination, an opioid and oxytocin as an acute <a href="https://www.earth.com/news/mindfulness-meditation-is-a-powerful-weapon-against-chronic-pain/" target="_blank" rel="noreferrer noopener">pain management</a> option, while at the same time lessening the likelihood of developing an addiction to opioids,” explained Dr. Meredith Berry.



Working alongside Dr. Yenisel Cruz-Almeida and Dr. Natalie Ebner, Dr. Berry is examining whether oxytocin can reduce pain effectively while also decreasing the desire for prolonged opioid use.



<h2 class="wp-block-heading" id="h-opioids-are-still-a-huge-problem">Opioids are still a huge problem</h2>



Opioid addiction has become a significant public health concern, particularly in the United States. 



Prescription opioids, while effective for managing pain, carry a high risk of addiction. Older adults, who often require pain management, can be particularly vulnerable.



By exploring alternatives that reduce pain without the same addictive potential, researchers hope to offer safer options for patients. 



Oxytocin's natural role in promoting well-being might counteract some of the addictive properties of opioids.



<h2 class="wp-block-heading" id="h-healing-addiction-with-oxytocin">Healing addiction with oxytocin</h2>



In their carefully designed study, the University of Florida team is working with participants aged 55 to 85 who have some history of opioid use. 



In a controlled setting, these participants will receive synthetic oxytocin via a nasal spray or a placebo after taking oral <a href="https://www.earth.com/news/experts-identify-a-route-to-safer-painkillers/" target="_blank" rel="noreferrer noopener">oxycodone</a>.



The researchers will collect data on how much the participants enjoy the drugs, as well as monitor physical responses like heart rate and breathing. 



They'll also assess cognitive and emotional reactions. To measure pain responses, they will apply mild mechanical pressure to the thighs and expose the hands to varying temperatures.



Dr. Ebner will analyze mood changes and cognitive effects, while Dr. Cruz-Almeida will examine how the drugs affect pain responses. 



Dr. Berry will evaluate the potential for reduced opioid addiction based on these findings. Physicians from the university's College of Medicine are involved to ensure participant safety.



<h2 class="wp-block-heading" id="h-is-oxytocin-the-wonder-drug-of-the-future">Is oxytocin the "wonder drug" of the future?</h2>



The combined efforts of these research teams highlight the versatility of oxytocin, putting the "love hormone" on the radar of scientists of all disciplines around the world.



From potentially enhancing memory and combating dementia to offering new strategies for pain management without the high risk of addiction, oxytocin's benefits could be far-reaching.



These studies underscore the importance of looking beyond traditional uses of well-known substances. Sometimes, the key to solving complex health issues lies in re-examining what we thought we knew.



The journey of oxytocin from a simple "love hormone" to a potential powerhouse in medical treatment is a testament to the ever-evolving nature of science. 



As researchers like Professor Saitoh and Dr. Berry continue their work, we can look forward to new discoveries that might improve the quality of life for many.



The full study was published in the journal <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0294113" target="_blank" rel="noreferrer noopener">PLOS One</a>.



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'Cuddle hormone' fosters love, boosts memory, and now also cures addiction

When we think of oxytocin, the image of a warm embrace or the deep connection between a mother and her child often comes to mind. This hormone, often dubbed the "love hormone" or "cuddle hormone," is famous for its role in fostering emotional bonds and promoting feelings of trust and empathy. But recent studies suggest that oxytocin might be doing much more behind the scenes, especially when it comes to how we learn and remember. And more surprisingly, it may also help cure addiction. Leading this exciting...

Leisure activities could help lower the risk of dementia, according to a new meta-analysis published in the online issue of <a href="http://www.neurology.org/">Neurology</a>, the medical journal of the <a href="https://www.aan.com/">American Academy of Neurology</a>. These activities include reading a book, doing yoga and spending time with family and friends.



For the investigation, the experts reviewed available studies on the effects of cognitive, physical, and social activities and the risk of dementia.



“Previous studies have shown that leisure activities were associated with various health benefits, such as a lower cancer risk, a reduction of atrial fibrillation, and a person’s perception of their own well-being,” said study co-author Lin Lu of Peking University Sixth Hospital in Beijing, China.&nbsp;



“However, there is conflicting evidence of the role of leisure activities in the prevention of dementia. Our research found that leisure activities like making crafts, playing sports or volunteering were linked to a reduced risk of dementia.”



The meta-analysis involved a review of 38 international studies involving more than 2 million people. The participants were followed for at least three years.



The individuals provided information on their leisure activities - those in which people engaged for enjoyment or well-being and were divided into mental, physical and social activities. During the study period, 74,700 people developed dementia.



The researchers found that, overall,&nbsp; leisure activities were linked to a reduced risk of dementia. Those who engaged in leisure activities had a 17 percent lower risk of developing dementia.



Mental activity included reading or writing for pleasure, watching television, listening to the radio, playing games or musical instruments, using a computer,&nbsp; and making crafts. The researchers found that people who participated in these activities had a lower risk of dementia by 23 percent.



Physical activities included walking, running, swimming, bicycling, playing sports, yoga, and dancing. Those who participated in these activities had a 17 percent lower risk of dementia.



Social activities referred to activities that involved communication with others and included attending a class, joining a social club, volunteering, visiting with relatives or friends, or attending religious activities. The experts found that people who participated in these activities had a seven percent lower risk of dementia.



There are plenty of activities that are easy to incorporate into our daily lives that have many benefits for the brain.&nbsp;



The study was supported by the Natural Science Foundation of China, China Association for Science and Technology and PKU-Baidu Fund.



Learn more about dementia at <a href="http://www.brainandlife.org/">BrainandLife.org</a>, home of the American Academy of Neurology’s free patient and caregiver magazine focused on the intersection of neurologic disease and brain health.&nbsp;



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By <a href="mailto:katherinebucko@gmail.com">Katherine Bucko</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Leisure activities greatly lower the risk of dementia

Leisure activities could help lower the risk of dementia, according...

The <a href="https://welcome.miami.edu/">University of Miami</a> Frost School of Music is about to embark on a new research study that will help at-risk mothers to engage with their <a href="https://www.earth.com/news/adult-bonobos-cry-like-babies-to-elicit-the-support-of-others/">babies</a> through singing. The research will be led by Shannon de l’Etoile, professor of Music Therapy at the school, and funded by the GRAMMY Museum Grant Program.



De l’Etoile is no stranger to the benefits of singing lullabies to babies. As a young music therapist in Colorado, she saw that when disadvantaged mothers were encouraged to sing to their babies, the positive responses they received were remarkable. She realized that music could be a powerful tool to help mothers learn more about their infants and to build a relationship with their new child.



In her previously published research, de l’Etoile states that: “Mothers around the world intuitively utilize and modify specific musical elements when singing to their infants. In response, infants show alterations in attention and arousal as well as clear preferences for their mothers' unique singing style.” De l’Etoile found that infant-directed singing has a number of benefits, most importantly that it helps babies learn to regulate their emotions. This, in turn, enables them to navigate socialization, school and the professional world more effectively, according to de l’Etoile, who has spent her career studying the habit.



“If a mother can sing in a way that captures the infant’s attention, it can help them tap into those brain structures that they need to develop for self-regulation,” said de l’Etoile, a board-certified music therapist and associate dean of graduate studies at the University of Miami’s Frost School of Music.



Infants appear to be biologically predisposed to perceive the nuances of music and this form of input can provide developmentally appropriate sensory stimulation. While singing to an infant comes naturally for most mothers, it is not as easy for mothers who find themselves in difficult circumstances. De l’Etoile has observed that mothers impacted by depression, domestic violence, or substance exposure may need encouragement and guidance to provide this unique form of caregiving.&nbsp;&nbsp;



“Infant-directed singing is a way that mothers communicate with their babies that most infants can recognize and respond to. But to be most effective, the mother needs to be attentive and sensitive to infant cues,” said de l’Etoile. “For some moms that may not be happening and that impacts the infant.”



De l’Etoile has been working with the College of Arts and Sciences Department of Psychology’s early intervention program at the&nbsp;<a href="https://www.fdlrs-um.miami.edu/">Linda Ray Intervention Center</a>&nbsp;to create a coaching program that will guide mothers in the practice of infant-directed singing. Her efforts have now received financial support from the&nbsp;<a href="https://www.businesswire.com/news/home/20220628005416/en/GRAMMY-Museum%C2%AE-Grant-Program-Awards-200000-for-Music-Research-and-Sound-Preservation">GRAMMY Museum</a>&nbsp;Grant Program, according to a news release from the University of Miami. Her program is one of just six scientific research projects that earned funding from the organization this year.



The Linda Ray Intervention Center has conducted cutting-edge research over the past three decades, focused specifically on the needs of children from birth to the age of two years. De l’Etoile’s new intervention program will be aimed at improving the developmental outcomes of at-risk infants by supporting their mothers to develop secure bonds with these infants, particularly through the use of infant-directed singing.&nbsp;



Through singing, mothers and infants demonstrate reciprocal behaviors considered necessary for the development of secure attachment, including maternal sensitivity and infant affect regulation. Consequently, infant-directed singing may serve as an effective treatment intervention for mothers and infants who are at-risk for insecure attachment.



“We want to give moms and caregivers these tools they can use, so that they can feel empowered to help their babies thrive,” de l’Etoile said. “Building self-regulation at an early age is so important because it helps children deal with adversity. Children who don’t regulate well are lacking in resilience, and they may have problems later in life, like obesity, addiction, and aggression.”



De l’Etoile and the center’s executive director, Isabel Chica, are now in the process of identifying and training staff members at the Center, who will coach mothers for a month in the most beneficial ways to sing to their infants. This will involve making video recordings of the mothers as they sing to their infants and then identifying how the mothers can be more sensitive to their infants’ emotions and also how they can assess if the infant is benefitting by observing how long it gazes at the mother.&nbsp;&nbsp;&nbsp;



“One of our main goals is to provide families with opportunities to learn new strategies and techniques that support positive parent-child interactions, and this pilot may strengthen parenting skills as well as a parent’s ability to help their child self-regulate,” Chica said. “We believe this is a great way for healthy attachments to develop between parent and child.”



In addition to analyzing videos of the mother-infant interactions, de l’Etoile will also work with the Frost School’s music engineering program to analyze recordings of the mother’s voice. She hopes the analysis will reveal changes over time in the mother’s ability to modify her singing according to the infant’s emotions, as well as in the extent to which the infant is engaged and comfortable.&nbsp;



“For an infant to make progress toward self-regulation, they need focused attention on the mother. And they also need to have achieved an optimal level of arousal where they are not excited, or fussy, but comfortable,” she said.



Both Chica and de l’Etoile are eager to begin with the training, now that they have spent more than two years working closely together to develop the program so that it aligns with the needs of the Center’s families.&nbsp;



“We want this project to have a lasting legacy and impact, not just for us to have positive outcomes but to create a model for how a program like this could be implemented in other early intervention facilities,” de l’Etoile said.



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By <a href="mailto:bosman@truewan.co.za">Alison Bosman</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Mothers can use singing to engage with infants

The University of Miami Frost School of Music is about...

A study from <a href="https://www.mcgill.ca/">McGill University</a> suggests that people are happier when money is not a major focus in their lives. The researchers found that individuals who live in communities where <a href="https://www.earth.com/news/too-much-emphasis-on-money-can-lead-to-social-isolation/">money</a> plays a minimal role report very high levels of happiness.

"Economic growth is often assumed to improve happiness for people in low income countries, although the association between monetary income and subjective well-being has been a subject of debate," wrote the study authors.&nbsp;

"We test this assumption by comparing three different measures of subjective well-being in very low-income communities with different levels of monetization."

"Contrary to expectations, all three measures of subjective well-being were very high in the least-monetized sites and comparable to those found among citizens of wealthy nations."

According to the researchers, less monetized societies are not usually included in global happiness surveys. The current study showed that the majority of people in these communities reported remarkably high levels of happiness.&nbsp;

In communities with the lowest levels of monetization, the experts documented a degree of happiness that is comparable to what is found in Scandinavian countries- which typically rate highest in the world.

"Our study hints at possible ways of achieving happiness that are unrelated to high incomes and material wealth," said study senior author Professor Eric Galbraith. "This is important, because if we replicate these results elsewhere and can pinpoint the factors that contribute to subjective well-being, it may help us circumvent some of the environmental costs associated with achieving social well-being in the least developed nations."

The findings indicate that high levels of subjective well-being can be achieved with minimal monetization, and contradict the idea that economic growth is linked to life satisfaction among low-income populations.

For the investigation, the researchers spent time in several small fishing communities with varying degrees of monetization in the Solomon Islands and Bangladesh, where citizens in both rural and urban areas a number of times. Overall, 678 people with an average age of 37 were interviewed.

The study revealed that in communities where money was in greater use, such as urban Bangladesh, residents reported lower levels of happiness.

"In less monetized sites, we found that people reported a greater proportion of time spent with family and contact with nature as being responsible for making them happy," explained study lead author Sara Miñarro. 

"But with increasing monetization, we found that the social and economic factors commonly recognized in industrialized countries played a bigger role. Overall, our findings suggest that monetization, especially in its early stages, may actually be detrimental to happiness."

The study is published in the journal <a href="https://journals.plos.org/plosone/">PLOS One</a>.

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By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Happiness comes easier when money is not a priority

A study from McGill University suggests that people are happier...

A new review study led by the <a href="https://www.uni-lj.si/university/">University of Ljubljana</a> in Slovenia has found that the record levels of physical inactivity and obesity among today’s children will have a negative impact on their health as temperatures rise globally, putting them at greater risk of developing heat-related health problems, such as dehydration, heat cramps, heat exhaustion, or heat stroke. Unfortunately, current <a href="https://www.earth.com/news/humanity-should-brace-for-catastrophic-climate-change/">climate change</a> policies fail to adequately address these issues and encourage children to make exercise part of their daily lives in order to increase their resilience to a hotter world.&nbsp;&nbsp;



By conducting a comprehensive review of over 150 medical and scientific studies on the relationship between children’s physical fitness and heat, study author Shawnda Morrison – an environmental exercise physiologist at the University of Ljubljana – discovered that overweight children were more than twice as likely to have difficulty regulating their body temperature than normal weight youngsters when exercising outdoors. In addition, she found that attendance at emergency departments in children’s hospitals was higher during hotter days, with younger children particularly likely to need emergency care.



The review also revealed that children’s aerobic fitness is currently 30 percent lower than that of their parents at the same age, while children’s physical activity levels have steadily declined worldwide, particularly over the last three decades. Most children are failing to meet <a href="https://www.who.int/">World Health Organization</a>’s guideline of performing at least one hour of physical activity each day – a problem further exacerbated by the lockdowns caused by the Covid-19 pandemic. According to Dr. Morrison, rising temperatures could further restrict children’s physical activity when parents perceive outdoor temperatures as “too hot to play,” making it more difficult for unfit children to maintain the physical activity levels needed to remain healthy.



“Fitter adults are better able to tolerate higher temperatures, due to a combination of physiological, behavioral, and psychological factors,” Dr. Morrison said. “Yet, as the world warms, children are the least fit they have ever been. It is imperative that children are encouraged to do daily physical activity to build up, and maintain, their fitness, so that they enjoy moving their bodies and it doesn’t feel like ‘work’ or ‘a chore’ to them.”



In order to solve these problems, parents and teachers should ensure that children engage in active play and structured games, and have access to physical education lessons in school. “Do what you love to do, whether it's a family bike ride or rollerblade, a stroll through the woods or walking the dog,” Dr. Morrison urged.&nbsp;



“Make sure the activity raises everyone's heart rate, enthusiasm, and positive energy and importantly, try not to completely avoid the heat but choose times of the day that are less hot (mornings/evenings) to keep active, since we need to keep ourselves moving in this new warming world,” she concluded.



The study is published in the journal <a href="http://dx.doi.org/10.1080/23328940.2022.2102375">Temperature</a>.



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By <a href="mailto:andrei.ionescu5891@gmail.com">Andrei Ionescu</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer&nbsp;&nbsp;

Global warming will compound health risks in children

A new review study led by the University of Ljubljana...

In a new study published by <a href="https://plos.org/">PLOS</a>, experts have taken a closer look at how <a href="https://www.earth.com/news/songbird-keeps-time-better-than-some-professional-musicians/">music</a> can help relieve acute pain. The researchers found that music-induced pain relief is greater when people feel they are in control of the song choices.



A team led by Dr. Claire Howlin of <a href="https://www.qmul.ac.uk/">Queen Mary University of London</a> demonstrated that individuals who are given the impression they have control over the music they hear seem to experience more pain relief than those who are not given this choice. 



Music is known to be therapeutic for chronic pain that lasts more than 12 weeks. However, the benefits for acute pain (less than 12 weeks) have remained unclear. The mechanisms which support the link between music and pain relief have also been a mystery.&nbsp;



A growing collection of research suggests that certain features of music, such as tempo, seem to be less important for pain relief. The current study indicates that perceived choice may be key.&nbsp;



"Music is increasingly being recognized as an adjuvant treatment for pain management," wrote the study authors. "Music can help to decrease the experience of both chronic and experimental pain. Cognitive agency has been identified as a specific mechanism that may mediate the analgesic benefits of music engagement however, it is unclear if this specific mechanism translates to acute pain."



"Previous attempts to understand the cognitive mechanisms that underpin music analgesia have been predominantly lab-based, limiting the extent to which observed effects may apply to participants’ everyday lives."



To investigate, Dr. Howlin and colleagues designed a study focused on 286 adults who were experiencing real-world acute pain. The participants were asked to rate their pain before and after listening to a music track that was composed in two different versions of varying complexity - low or high.&nbsp;



The individuals were randomly assigned to hear one or the other version of the track, and some were given the (false) impression that they had control over which version they heard.&nbsp;



The study revealed that participants who felt they had control over the music experienced greater relief in the intensity of their pain than participants who had no perceived control.&nbsp;



Furthermore, individuals who reported being more engaged with music in their everyday life experienced even greater pain-relief benefits from having a sense of control.



“Now we know that the act of choosing music is an important part of the well-being benefits that we see from music listening," said the study authors. "It’s likely that people listen more closely, or more carefully when they choose the music themselves.”



The study is published in the journal <a href="https://journals.plos.org/plosone/">PLoS ONE</a>



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By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Music provides pain relief when patients choose the tunes

In a new study published by PLOS, experts have taken...

Air <a href="https://www.earth.com/news/air-pollution-increases-the-risk-of-dementia/">pollution</a> has been linked, in past research, to increased risks of neurological disorders, such as schizophrenia&nbsp;and&nbsp;autism. Considering that 99 percent of people across the globe live in cities where air quality is questionable, it is surprising that only one in 44 children is diagnosed with autism. Naval oceanographer Carina Block worked where she was exposed to jet exhaust fumes every day while she was pregnant and when she gave birth to a baby with a neurodevelopmental problem, she thought there might be a connection.



“I was pregnant, stressed, and worked near planes,” Block recalled. “I walked past jet fuel exhaust every day. And my child ended up developing a neurodevelopmental disorder, hydrocephalus.”



Although her daughter is now healthy, Block has continued to follow her hunch by conducting research under the auspices of the labs of psychology and neuroscience professor Staci Bilbo, PhD and cell biology professor Cagla Eroglu, PhD, both from <a href="https://duke.edu/">Duke University</a> in North Carolina. Block’s most recent research on the effects of air pollution and stress on the offspring of mice provides convincing evidence that, had she been carrying a baby boy, he may well have been born with autism



The research involved exposing pregnant mice to air pollution in the form of diesel exhaust particles. Towards the end of their pregnancy, the mice moms were dealt another stressor: they were given insufficient material from which to build a nest for their pups. According to the researcher, this added stress mimics the situation that many people find themselves in during the course of their normal lives.&nbsp;



When asked why not every child born in a polluted city develops autism, Bilbo explained that environmental toxins are worse for some people than for others and it's always the most vulnerable populations that are affected.&nbsp; In the case of autism and air pollution, Bilbo thinks the missing link is maternal stress stemming from poverty and housing insecurity.



“It’s not that wealthy people aren't stressed,” Bilbo said. “But it’s different when you have to worry about where you're going to live and whether you're safe in your home.”



This explains why Block and her team chose to limit the amount of nesting material to the pregnant mice that were already exposed to polluted air. They wished to test this combination of conditions, which are endured by many people every day, in order to monitor the effects on the brain development of the offspring.&nbsp;



The findings, published in the journal <a href="https://www.cell.com/cell-reports/home">Cell Reports</a>, showed that although the stressed mice were exemplary parents that nursed and groomed their pups just as much as those who were spared the prenatal stressors, their male offspring exhibited unusual, autism-like social behavior. Adolescent male mice born to stress- and smog-exposed moms preferred hanging out with a yellow rubber duck rather than a nearby mouse (mice usually prefer the company of one of their own rather than that of a bath toy). Female offspring were less likely to be affected in this way.&nbsp;



After observing the unusual behavior in male offspring, Block and her team looked at what had happened in their brains that may have made them socially shy. Specifically, the research team wondered whether male brains had somehow missed out on their necessary refinement early in development.



All young animals have an excess of connections (synapses) between their brain cells. As they grow up and develop, these connections get “pruned” back; connections that are used often are strengthened while connections that are seldom used are removed.&nbsp; The result of this process of synaptic pruning is that the brain becomes more efficient as the animal ages.&nbsp;



The results of the brain analysis of mice indicated that male offspring of stressed mothers who had inhaled diesel fumes had missed out on the normal pruning of synapses in the anterior cingulate cortex (ACC), a brain region that is important for perceiving and producing social cues. The overabundance of synapses in this region seemed to explain their shy social tendencies as teenagers, but it left open the question of how a double-hit of smog and stress during gestation halts typical brain sculpting.



In order to understand this, Block and her team looked at the immune system, specifically at immune cells in the brain, called microglia. These are highly active cells that monitor the brain constantly for pathogens such as viruses and bacteria, but they also destroy weak or dead synapses. This helps to trim away unwanted connections and keep the brain tidy. Block reasoned that if there are more synapses than usual, perhaps there aren’t as many microglia in the brains of affected males.



Confusingly, Block found that adolescent males from the stressed mother mice had just as many microglia in the ACC as did their peers from non-stressed moms. However, smog and housing stress lead to microglia having less of the protein that stimulates their appetite for synapses, which likely explains why pruning did not take place effectively in the ACC.&nbsp;



By adulthood, the situation in the mouse brains had been reversed. Males from smog- and stress-exposed moms now had fewer synapses in their ACC and were more gregarious than their unexposed peers. This atypical tendency to be more outgoing rather than reserved mirrored the&nbsp;<a href="https://today.duke.edu/2022/03/duke-scientists-find-brain-network-makes-mice-mingle">behavior and brain activity of mice with autism-linked genes</a>&nbsp;that has been recently described by Block’s collaborator and co-author, Duke neurobiology professor and psychiatrist Kafui Dzirasa, MD, PhD.



Dzirasa states that many of his patients with autism would fail the standard lab tests used to diagnose mice, because mouse behavior is considered to be autism-like if the mice are less inclined to socialize. Dzirasa and Block say that people with autism are not inherently introverted, but have difficulty understanding social cues and conventions rather than being unwilling to interact socially.&nbsp;



Block and Bilbo suggest this work provides a clear mechanism in mice that may explain why high levels of air pollution&nbsp;<a href="https://journals.lww.com/environepidem/Fulltext/2019/10000/Air_pollution,_neighborhood_deprivation,_and.8.aspx">increase the likelihood that a child will develop autism</a>&nbsp;only if they’re born in a poor neighborhood. It might also lead to the development of drugs to help prevent microglia from being manipulated by environmental stressors, since diesel exhaust and housing stress triggers a similar immune response when pregnant women catch the flu.



For now, Bilbo and her team hope that this unequivocal evidence about the impact of stress and air pollution during pregnancy pushes policymakers to promote legislation supporting clean air initiatives and social services, such as improved and expanded public housing.



“You can't ignore this study’s mechanistic findings,” Bilbo said. “This is happening, and this is how.”



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By <a href="mailto:bosman@truewan.co.za">Alison Bosman</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Is autism related to pollution and stress during pregnancy?

Air pollution has been linked, in past research, to increased...

Previous studies have shown that <a href="https://www.earth.com/news/a-daily-dose-of-nature-can-improve-your-diet/">nature</a> is important for physical and mental health. But, there is a gap in the research, as experts have yet to determine which aspects of nature (e.g., smells, sounds, colors) impact well-being and why.



A new study led by the <a href="https://www.kent.ac.uk/">University of Kent</a> has shed some light on the subject. The researchers concluded that the scents we experience in nature help us feel less anxious and more cheerful.&nbsp;



The study was carried out in a woodland environment during February, April, June, and October of 2019. The researchers found that the participants did not necessarily experience a connection with the scent of the woodlands. Rather, they associated the smells in the woodlands with notable events in their lives, prompting emotional responses to the memory.



Think of fresh cut grass, which might bring back feelings of summer vacation as a child and the freedom that came with it. Participants mentioned that the smell of pine trees reminded them of Christmas.&nbsp;



Interestingly, people also felt more relaxed in the absence of scent. The experts believe this is due to the many unpleasant odors encountered in urban environments. The absence of these smells represents "fresh air" or the removal of pollution, so people find it pleasant.&nbsp;&nbsp;



"We found smells affected multiple domains of well-being with physical well-being discussed most frequently, particularly in relation to relaxation, comfort, and rejuvenation," wrote the researchers. "Even absence of smell was perceived to improve physical well-being, providing a cleansing service, removing the pollution and unwanted smells associated with urban areas, therefore enabling relaxation."



Public health professionals may consider these findings especially relevant since relaxation relieves stress and lowers cortisol levels which are associated with various diseases.



Study co-author Dr. Jessica Fisher is a postdoctoral research associate at Kent's Durrell Institute of Conservation and Ecology (DICE).



"The study provides findings that can inform the work of practitioners, public health specialists, policy-makers and landscape planners looking to improve wellbeing outcomes through nature. Small interventions could lead to public health benefits," said Dr. Fisher.



The researchers point out that people of different cultures will not experience smells in the same ways and encourage further studies to investigate how age and different landscapes affect scent interpretation.&nbsp;&nbsp;



The study is published in the journal <a href="https://link.springer.com/article/10.1007/s13280-022-01760-w">Ambio</a>.



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By <a href="mailto:nire518@gmail.com">Erin Moody </a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Smells in nature help us feel more relaxed and cheerful

Previous studies have shown that nature is important for physical...

Scientists have long known that prolonged <a href="https://www.earth.com/news/showing-signs-of-stress-could-make-you-more-likeable/">stress</a> can have negative effects on the body, including premature aging, early mortality, chronic disease, depression, and overall poor quality of life. Moreover, stress can also affect the hair, by releasing hormones that change hair pigmentation, turning it gray or white, or cause hair loss. Now, a team of researchers led by the <a href="https://english.hi.is/university_of_iceland">University of Iceland</a> and the <a href="https://www.insp.mx/insp-overview.html">National Institute of Public Health of Mexico</a> has found that stress levels are also reflected in how much of the hormone cortisol is stored in hair.



The scientists analyzed hair samples from over 1,200 women from Iceland and Mexico and asked them to fill in a psychological questionnaire measuring their stress perception. The analysis revealed a linear relationship between the women’s perceived stress and the cortisol levels in their hair: the higher they scored on the stress scale, the more cortisol they had in their hair, with one additional point on the scale corresponding on average to a 1.4 percent increase in hair cortisol levels. Women who scored the highest tended to be less likely to be employed, married, or have a graduate degree, and more likely to be obese and smokers, suggesting that these lifestyle and environmental pressures can play a significant role in fostering stress.



“Despite relatively small absolute differences, an association between perceived stress and hair cortisol concentration was found in a sample of women from two diverse geographical and cultural backgrounds supporting the hypothesis that hair cortisol concentration is a viable biomarker in studies of chronic psychological stress,” the study authors wrote.



Although the researchers observed small distinctions between the two groups of women living on two different continents and most likely experiencing different stressors, the similarities were stronger, suggesting that stress levels are indeed correlated with hair cortisol concentrations. However, since only women were involved in the study, further research is needed to determine how gender differences play into the stress-cortisol axis. Moreover, long-term studies investigating how cortisol in the hair changes over time as stress waxes and wanes are also crucial for clarifying the health impact of chronic stress.



The study is published in the journal <a href="https://journals.plos.org/globalpublichealth/article?id=10.1371/journal.pgph.0000571">PLoS Global Public Health</a>.



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By <a href="mailto:andrei.ionescu5891@gmail.com">Andrei Ionescu</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer&nbsp;&nbsp;&nbsp;

Stress is reflected in hair cortisol levels

Scientists have long known that prolonged stress can have negative...

Bonobos (Pan paniscus) are our closest living primate relatives and share more than 98 percent of their DNA with us. They are also among the most vocal of the great apes, using around 15 different call types to <a href="https://www.earth.com/news/life-experience-shapes-the-way-dogs-communicate-with-humans/">communicate</a> particular emotional states, such as screaming, threat barks, greetings and alarm calls. For a long time, it was thought that great apes had no control over their emotional expressions but made them instinctively in response to the specific emotional state.



However, a new study of captive bonobos in the Democratic Republic of Congo has revealed an altogether different situation. Psychologists at <a href="https://www.durham.ac.uk/homepage/">Durham University</a> have found that adult bonobos use “baby-like” distress calls to curry favor with group members after a conflict. The calls are often accompanied by other behavior typical of&nbsp;baby bonobos, such as pouting, whimpering and throwing tantrums.&nbsp;



The researchers suggest that these calls are used strategically to reduce the chances of another conflict with the opponent, and to elicit comforting behavior from others in the group. The adult bonobos usually stop signaling their distress in this way once they receive support from other adults, whereas immature bonobos will continue to call even after they have been consoled.&nbsp;



The study, published in the <a href="https://royalsocietypublishing.org/journal/rstb">Philosophical Transactions of the Royal Society B, Biological Sciences</a>, was based on research carried out on two bonobo groups (over 40 individuals) at the Lola ya Bonobo Sanctuary in Kinshasa (Democratic Republic of Congo), the world’s only bonobo sanctuary.&nbsp;



The researchers examined how bonobo victims communicate about their distress after a fight, and whether these signals affect the responses of bonobo bystanders. The findings indicated that adult bonobos were less likely to be re-attacked after a conflict with an opponent if they displayed behavior and made calls typical of baby bonobos. They were also more likely to elicit a comforting response from the bystanders.



The analysis also showed that a bonobo is sensitive to who is present in the audience when it is attacked, and will display more signals in general if more bonobos in the social audience are nearby. This suggests bonobos adapt their communication signals depending on which individuals are in the close vicinity. The results thus indicate that expressions of emotion are not simply instinctual read-outs of internal states but can be used in flexible and strategic ways to manipulate others and purse social goals.&nbsp;



“Bonobos are highly sensitive to social situations and who is surrounding them. They have rich emotional lives and are able to communicate their emotional states in flexible ways to influence their group members," said study lead author Dr. Raphaela Heesen



“In using specifically “baby-like” signals, bonobos might increase their chances to be consoled by others and alleviate their own stress level following aggressive attacks. Our research shows that emotions and their expression do not only play a role in the regulation of social life in our own species, but also in our closest living primate relatives.”



“The act of comforting a victim in distress has long been considered a form of empathy that is initiated by the bystander. However, our study reveals that the victim’s own signals may be used strategically to shaping these responses," said study senior author Dr Zanna Clay.



“By producing signals that make them seem more like infants, bonobo victims can promote the chances of receiving comfort from others. This highlights the important role that communication plays in shaping empathic responding."



The researchers thus emphasize that bonobos have flexible ways of communicating their emotions, just like humans. The study sheds light on understanding the emotional life of these animals with a focus on the potential evolutionary origins of the communication of emotions.



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By <a href="mailto:bosman@truewan.co.za">Alison Bosman</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Adult bonobos cry like babies to elicit the support of others

Bonobos (Pan paniscus) are our closest living primate relatives and...

Social isolation and loneliness are two different constructs. A person can be socially isolated but not feel lonely or, conversely, can feel lonely despite not being socially isolated. Both social isolation (the objective state of having few or infrequent social contacts), and loneliness (perceived isolation that causes stress) are associated with adverse <a href="https://www.earth.com/news/plant-based-foods-are-healthier-than-animal-products/">health</a> outcomes.&nbsp;



In a new review article, a scientific committee writing on behalf of the <a href="https://www.heart.org/">American Heart Association</a> has summarized the observational and intervention research that examines the impact of social isolation and loneliness on cardiovascular and brain health. The experts conducted a systematic review of recent research available on four databases, namely PubMed, PsycInfo, Cumulative Index of Nursing and Allied Health, and Scopus.&nbsp;



Dr. Crystal Wiley Cené is the chair of the writing group for the scientific statement, and professor of clinical medicine and chief administrative officer for health equity, diversity and inclusion at the University of California San Diego Health.



“Over four decades of research has clearly demonstrated that social isolation and loneliness are both associated with adverse health outcomes,” said Dr. Cené. “Given the prevalence of social disconnectedness across the U.S., the public health impact is quite significant.”



The experts found that social isolation and loneliness are associated with an increase of about 30 percent in the risk of <a href="https://www.heart.org/en/health-topics/heart-attack">heart attack</a>&nbsp;or&nbsp;<a href="https://www.stroke.org/en/">stroke</a>, or of death from either cause.&nbsp;They state that social isolation becomes more of a problem with age, because of factors such as retiring or losing a life partner. It is estimated that nearly one quarter of U.S. adults aged 65 and older are socially isolated, and the prevalence of loneliness is even higher, with estimates of between 22 percent and 47 percent.



Even though older people are more likely to experience social isolation and loneliness, this does not mean that young people are immune. A survey from Harvard University’s Making Caring Common project describes “Gen Z” (adults currently ages 18-22) as the loneliest generation.&nbsp;



Increased isolation and loneliness among younger adults may be attributed to higher social media use and less engagement in meaningful, in-person activities. COVID-19 has probably also played a role in making younger people feel more disconnected from society, and has also disproportionately affected older adults, women and low-income individuals.



The writing group that reviewed research on social isolation published up until July 2021 found the following:



<ul><li>Social isolation and loneliness are common, yet under-recognized determinants of cardiovascular and brain health.</li><li>Lack of social connection is associated with increased risk of premature death from all causes, especially among men.</li><li>Isolation and loneliness are associated with elevated inflammatory markers, and individuals who were less socially connected were more likely to experience physiological symptoms of chronic stress.</li><li>In assessing risk factors for social isolation, the relationship between social isolation and its risk factors goes both ways: depression may lead to social isolation, and social isolation may increase the likelihood of experiencing depression.</li><li>Social isolation during childhood is associated with increased cardiovascular risk factors in adulthood, such as obesity, high blood pressure and increased blood glucose levels.</li></ul>



“There is strong evidence linking social isolation and loneliness with increased risk of worse heart and brain health in general; however, the data on the association with certain outcomes, such as heart failure, dementia and cognitive impairment is sparse,” said Dr. Cené.



The evidence is most consistent for a link between social isolation and loneliness, and death from heart disease and stroke, with a 29 percent increase in the risk of heart attack and/or heart disease death, and a 32 percent increased risk of stroke and stroke death. “Social isolation and loneliness are also associated with worse prognosis in individuals who already have coronary heart disease or stroke,” noted Dr. Cené.



The researchers found that people with heart disease, who were socially isolated, had a two- to three-fold increase in risk of death during a six-year follow-up study. Socially isolated adults with three or fewer social contacts per month may have as much as a 40 percent increased risk of recurrent stroke or heart attack. In addition, the chance of surviving for at least five years after heart failure was lower (60 percent) in people who were socially isolated, and for those who were both socially isolated and clinically depressed (62 percent). This was in comparison with five-year survival rates in those who have more social contracts and are not depressed (79 percent).



Social isolation and loneliness are also associated with other behaviors that negatively impact cardiovascular and brain health, such as lower levels of self-reported physical activity, eating less fruit and vegetables, and spending more time sitting. In addition, many large studies found significant associations between loneliness and a higher likelihood of smoking.



“There is an urgent need to develop, implement and evaluate programs and strategies to reduce the negative effects of social isolation and loneliness on cardiovascular and brain health, particularly for at-risk populations,” said Dr. Cené. “Clinicians should ask patients about the frequency of their social activity and whether they are satisfied with their level of interactions with friends and family. They should then be prepared to refer people who are socially isolated or lonely – especially those with a history of heart disease or stroke – to community resources to help them connect with others.”



The current review highlights research aimed at reducing social isolation and loneliness among older adults. These studies found that fitness programs and recreational activities at senior centers, as well as interventions addressing negative thoughts of self-worth and other negative thinking, have shown promise in reducing isolation and loneliness.



The review did not identify any research that tested possible interventions to mitigate the adverse impacts of social isolation or loneliness on cardiovascular or brain health specifically.



&nbsp;“It is unclear whether actually being isolated (social isolation) or feeling isolated (loneliness) matters most for cardiovascular and brain health because only a few studies have examined both in the same sample,” said Dr. Cené. “More research is needed to examine the associations among social isolation, loneliness, coronary heart disease, stroke, dementia and cognitive impairment, and to better understand the mechanisms by which social isolation and loneliness influence cardiovascular and brain health outcomes.”



The findings are published in the form of a scientific statement in the <a href="https://www.ahajournals.org/journal/jaha">Journal of the American Heart Association</a>, an open access, peer-reviewed journal.



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By <a href="mailto:bosman@truewan.co.za">Alison Bosman</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Loneliness is an underestimated threat to heart health

Social isolation and loneliness are two different constructs. A person...

Having a sense of control over our lives has been shown to influence how well we feel, how healthy we are, and how successful we are at mastering challenges in our lives. Some people have high internal control beliefs and feel they can influence their environment and their future by their own <a href="https://www.earth.com/news/pandemic-restrictions-had-a-lasting-effect-on-behavior-patterns/">behavior</a>. Others, with high external control beliefs, perceive that things happen to them as a result of external factors, such as powerful others, chance and fate.&nbsp;



Being involved in a romantic relationship can have a powerful influence on a person’s perception of control, often being linked to improvement in subjective well-being. Although previous research has investigated the links between perceived control and satisfaction with a romantic relationship, little is known about how a person’s perceived control changes due to the loss of such a relationship.&nbsp;



New research by Eva Asselmann of the Health and Medical University in Potsdam, Germany, and Jule Specht of Humboldt-Universität zu Berlin has now investigated the changes in perceived control that people experience after going through a separation, a divorce or the death of a partner. The findings are published in the open-access journal&nbsp;<a href="https://journals.plos.org/plosone/">PLOS ONE</a>.



For their study, the researchers used data from the Socio-economic Panel Study (SOEP), a nationally representative household panel study conducted in Germany. This study commenced in 1984 and is ongoing to this day. Specifically, they used yearly questionnaire results from 1994, 1995, and 1996 to evaluate changes in perceived control for 1,235 people who experienced separation from their partner, 423 who got divorced, and 437 whose partners passed away.



Statistical analysis of the questionnaire results suggests that, overall, people who went through a separation experienced a decrease in perceived control in the first year after separation, but this was followed by a gradual increase in the subsequent years. Interestingly, the authors report that individuals who separated from a partner had higher external control beliefs in the first year of being separated, but their internal control beliefs (sense that they could control the outcomes of their own lives) increased in the following years.&nbsp;



After separation, women were more likely than men to have a decreased sense of control, and younger people experienced less of a decrease in their perceived control than did older people who became separated from their partners.&nbsp;



The findings were different in the case of people whose partners had passed away. In general, people whose partners passed away had an overall increase in perceived control during the first year following the loss. Thereafter, perceived control continued to increase, when compared with levels before the loss was experienced. The authors suggest that after losing a partner, many people may realize that they are able to cope with life on their own and this would lead to a new sense of autonomy and independence.&nbsp;



There was again an age effect in changes to perceived control after experiencing the death of a partner, with younger people reporting more detrimental effects on their sense of control than older people did.&nbsp;



The analysis found no links between getting divorced and a person’s perceived sense of control. Getting divorced was thus considered to be unrelated to changes in perceived control in the years surrounding the event.&nbsp;



The researchers acknowledge that there are some limitations to their study, not least of which is the fact that perceived control was assessed in the questionnaires with a scale that made use of only eight items. More comprehensive data on this aspect in future studies would be an improvement. The researchers also call for future investigations to track people who have not yet experienced relationship loss and then to evaluate changes in perceived control when loss occurs. They also call for research into the mechanisms that underlie post-loss changes in perceived control.



“Our findings suggest that people sometimes grow from stressful experiences – at least regarding specific personality characteristics. In the years after losing a romantic partner, participants in our study became increasingly convinced in their ability to influence their life and future by their own behavior," explained the study authors. "Their experience enabled them to deal with adversity and manage their life independently, which allowed them to grow.”



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By <a href="mailto:bosman@truewan.co.za">Alison Bosman</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Relationship loss can lead to renewed sense of control

Having a sense of control over our lives has been...

Anxiety is the most common mental health condition in young people in Australia, affecting up to 31.5 percent of the population between 16 and 24 years of age. This is double the rate of prevalence in the general population. Characterized by feelings of extreme worry and concern that are not necessarily related to any specific cause, anxiety can have severe manifestations that interfere with a person’s ability to function effectively.



Treatments used to decrease the severity of symptoms in young people suffering from anxiety include cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitor (SSRI), which is an antidepressant drug. Unfortunately, these approaches only work for about 50 percent of young people, and the rest continue to suffer the debilitating symptoms of their anxiety disorder.&nbsp;



It is this situation that led <a href="https://www.orygen.org.au/">Orygen</a>, Australia's&nbsp;first and only youth mental health policy think tank, to undertake a pilot study on the use of cannabidiol (CBD) to treat anxiety in treatment-resistant young people. The Cannabidiol Youth Anxiety Pilot Study (CAPS) was a 12-week open-label trial initiated by Orygen with the aim to test the feasibility, safety, tolerability and therapeutic effects of cannabidiol in reducing anxiety severity in young people.



“We’re seeing more and more young people experiencing anxiety – it’s the fastest growing form of mental ill-health in young people and we urgently need innovation in treatment. Cannabidiol is a promising treatment option which appears safe and effective. We need further research to confirm this and explore its value,” said Professor McGorry, study co-investigator and Orygen Executive Director.



Cannabidiol is a non-intoxicating component of the&nbsp;Cannabis sativa&nbsp;plant. This means it is not mind-altering and will not make a person “high." It is also not addictive and does not induce any significant negative side effects or lead to the emergence of any neurological or psychiatric manifestations. Previous research has already found CBD to be effective in reducing symptoms of anxiety in adults.&nbsp;



In Australia, cannabidiol has been approved by the Therapeutic Goods Administration as a treatment for children with rare forms of epilepsy (Dravet syndrome and Lennox Gastaut syndrome). It has also been approved for clinical trials as a treatment for children in Australia with Tourette Syndrome, Fragile X syndrome, autism spectrum disorder and intellectual disability.



“Cannabidiol is non-intoxicating and doesn’t contain tetrahydrocannabinol (THC) so it doesn’t cause alterations in thinking and perception, it doesn’t make you ‘high’ and it’s not addictive. In fact, cannabidiol has been used to treat addictive behaviors in other research trials and can reduce some of the adverse and intoxicating effects of THC,” said Orygen’s Professor Paul Amminger, who led the study.



Thirty young people took part in the trial. They were all clients of Orygen’s primary care services, and were aged between 12 and 25 years. All the participants had been diagnosed with an anxiety disorder and had failed to show significant improvement in their symptoms after five cognitive behavioral therapy sessions. They began the trial by taking a 200mg capsule of cannabidiol each day, and increased this to 400mg after one week. Those who did not show improvement at this dosage had their dosage increased in 200mg increments until they received 800mg per day.



Participants had to fill in a questionnaire about the severity of their symptoms, such as panic attacks, situational anxieties, worries and flashbacks. This questionnaire provided a self-rated scale (the Overall Anxiety Severity and Impairment Scale) that quantified the anxiety symptoms they experienced. In addition, a clinician completed a Hamilton Anxiety Rating for each participant.



The results of the pilot study, published in the <a href="https://www.psychiatrist.com/jcp/">Journal of Clinical Psychiatry</a>, showed that after 12 weeks, young people with treatment-resistant anxiety had an average of 42 percent reduction in the severity of their symptoms. This result was evident using data from both the clinician’s rating assessment and the participant’s own self-assessment.&nbsp;&nbsp;



“The young people had fewer panic attacks and could do things which they were previously unable to do like leave the house, go to school, participate in social situations, eat at restaurants, take public transport or attend appointments by themselves,” Professor Amminger said. “That's an amazing change in the group which has had treatment-resistant, long-standing severe to very severe anxiety."



Professor Patrick McGorry said the findings held promise for a significant number of young people, with Australian Bureau of Statistics&nbsp;<a href="https://www.abs.gov.au/statistics/health/mental-health/national-study-mental-health-and-wellbeing/latest-release">data released recently showing </a>that anxiety was the most common form of mental ill-health in young people in the country.&nbsp;



“Our pilot study found that cannabidiol not only helped to reduce anxiety symptoms but it was also very well tolerated&nbsp;–&nbsp;the most common side-effects were mild sedation and mild fatigue but that was at the time when doses were increased, and usually went away after a couple of days,” said Professor Amminger. “We did not see side-effects like suicidal thoughts, irritability or sleep problems, which are not uncommon in people taking SSRIs.”



Although the findings are promising, further research is required.



“An open-label pilot study is limited by its design,” Professor Amminger explained. “To see a treatment effect in the treatment-resistant group is encouraging, but it could still be a placebo effect. The next step is a randomized controlled trial, which is the gold standard to test a new intervention. Such a trial needs to be done in a much larger group – around 200 to 250 young people – to enable us to say with some certainty that there is, or is not, a real treatment benefit and effects.”



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By <a href="mailto:bosman@truewan.co.za">Alison Bosman</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Cannabidiol is effective for treating anxiety in young people

Anxiety is the most common mental health condition in young...

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features Nushagak Bay, a large estuary in southwest Alaska. Nushagak runs mainly north to south and exits in Bristol Bay, a large body of water in the Bering Sea.



"The bay is primarily fed by the Nushagak River, which begins in the Alaska Range and flows southwest approximately 450 km. The bay is also fed by several additional rivers including the Wood, Igushik, Snake and Weary rivers," says ESA.



"The dark colors of the Nushagak River are most likely due to tannins or lignins (chemical substances found in plants). Tannins and lignins from roots, leaves, seeds, bark and soil can leach into the water and give it a brown or even black colour. The sediments then flow southwards where it is mixed with the bluer waters of the bay."



Video/ Image Credit: ESA



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By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Nushagak Bay in southwest Alaska

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Today's Video of the Day from the <a href="https://www.acs.org/">American Chemical Society</a> (ACS) reveals that proteins on flu viruses are actually flexible, tilting and waving in a “breath-like” motion. According to the experts, these proteins could be used to better defend against the flu.



"The main antigenic targets of influenza virus are two surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA). Whereas the structural and dynamical properties of both glycoproteins have been studied previously, the understanding of their plasticity in the whole-virion context is fragmented," wrote the researchers.



To investigate, the team conducted detailed simulations of the influenza A H1N1 virion, or the swine flu. The experts concluded that the visualizations show many new vulnerable states of flu viruses, which could improve future vaccines and antiviral drugs.



Video/ Image Credit: American Chemical Society&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Flu viruses are more flexible than expected

[sendtonews key="G9bUoxcjr4-2511624-12187" type="single"] Today's Video of the Day from the...

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features Lake Trasimeno, which is located west of Perugia in central Italy. It is the fourth largest lake in the country. While Trasimeno’s water level varies, it has a maximum depth of approximately six meters.&nbsp;



"In this Copernicus Sentinel-2 image, captured on 6 August 2022, the lake’s emerald green colour is likely due to the presence of phytoplankton. Streaks in the water, particularly visible in the west, indicate the presence of soil and sediments which have been stirred up by winds. Dark colored waters in the southern part of the lake indicate a presence of submerged and floating macrophytes (aquatic plants) as well as algae," says ESA.



"Surrounded by hills on three sides, Trasimeno is subject to heavy storms created by winds, especially from the north and west. There are three islets in the lake: Maggiore, Minore and Polvese (the largest). The lake’s shores are sparsely inhabited with only two popular villages: Castiglione del Lago and Passignano sul Trasimeno."



"Italy is experiencing its worst drought in 70 years which has affected drinking water supplies, hydroelectric power and agricultural production. High temperatures, hot winds and lack of rainfall are the main causes of drought in the Umbrian region which saw Lake Trasimeno’s drop 1.3 m, reaching the limit of the hydrometric zero in July 2022."



Video/Image Credit: ESA&nbsp;



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By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Lake Trasimeno in Central Italy

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Today's Video of the Day from the <a href="https://www.acs.org/">American Chemical Society</a> describes a new self-powered nanosensor that can instantly detect mercury contamination with the tap of a finger.&nbsp;



The oxidized form of mercury can be harmful when it is ingested through contaminated water or food. This makes it necessary for experts to develop sensors that can quickly and accurately detect the presence of mercury.&nbsp;



Zong-Hong Lin and colleagues have now created a triboelectric nanosensor (TENS) that can detect mercury by simply by touching a sample. According to the researchers, their TENS could serve as the basis for similar devices to safely and remotely monitor other pollutants.



Video Credit: American Chemical Society&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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Detecting mercury contamination with the tap of a finger

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Today’s Video of the Day from the <a href="https://www.acs.org/">American Chemical Society</a> explores the ability of salt to transform the way that foods and beverages taste. Salt is known to cover up undesirable flavors, such as bitterness in coffee or beer, but how exactly does sodium chloride change the taste of other compounds?



One previous study showed that, not only does salt suppress bitterness, but also enhances sweetness and sourness. Another study revealed that bitterness reduction by salt seems to be happening at the tongue receptor level as well as in the brain.&nbsp;



While it is known that salt taste is mediated by the presence of sodium channels in the form of taste buds, experts believe that there is also an unknown receptor responsible for how we taste salt that has not yet been identified.&nbsp;



Video Credit: ACS Reactions



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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How does salt makes things taste better?

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features Santiago, the capital city of Chile. The city is located in the center of the Santiago Metropolitan Region, which has a population of about eight million people.&nbsp;



'The weather of Santiago resembles the Mediterranean climate with dry and warm summers with temperatures reaching up to 35°C (from October to March) and cool and humid winters that can drop to 0°C (from April to September)."



"The city lies in the centre of the country’s central valley around 80 km from the Pacific Ocean to the west and borders Argentina to the east. A tiny part of Argentina is visible in the top-right corner of the image where the mountain crest of the Andes Mountains acts as a divider between the two countries," says ESA.



Video/ Image Credit: ESA



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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Santiago, Chile in South America

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Spiral,Galaxy,,Illustration,Of,Milky,Way

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Astronomers at <a href="https://www.jhu.edu/">Johns Hopkins University</a> have created an interactive map of the universe, including the actual position and real colors of 200,000 galaxies. The map allows the public to access data that was previously only available to scientists.



The map was developed using data collected by the Sloan Digital Sky Survey. For over two decades, a telescope in New Mexico was aimed at slightly different locations to capture the night sky.&nbsp;



"Growing up I was very inspired by astronomy pictures, stars, nebulae and galaxies, and now it's our time to create a new type of picture to inspire people," said map creator Brice Ménard, a professor at Johns Hopkins. "Astrophysicists around the world have been analyzing this data for years, leading to thousands of scientific papers and discoveries. But nobody took the time to create a map that is beautiful, scientifically accurate, and accessible to people who are not scientists. Our goal here is to show everybody what the universe really looks like."



"In this map, we are just a speck at the very bottom, just one pixel. And when I say we, I mean our galaxy, the Milky Way which has billions of stars and planets. We are used to seeing astronomical pictures showing one galaxy here, one galaxy there or perhaps a group of galaxies. But what this map shows is a very, very different scale."



"From this speck at the bottom, we are able to map out galaxies across the entire universe, and that says something about the power of science."



The <a href="https://mapoftheuniverse.net/">interactive map</a> is available online, where it can be downloaded for free.



Video Credit: Johns Hopkins&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



Check us out on <a href="https://www.earth.com/earthsnap/">EarthSnap</a>, a free app brought to you by Eric Ralls and Earth.com.

Interactive map of the universe includes 200,000 galaxies

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Lesotho: Africa's "Kingdom in the Sky" Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features northwest Lesotho in South Africa.



According to ESA, Lesotho is the only nation in the world that lies completely above 1,000 m in elevation. The country is famous for its tall mountains and narrow valleys, and is known as Africa's "Kingdom in the Sky."



Out of a population of around two million people, about 80 percent live in rural areas. More than 75 percent of these people are engaged in <a href="https://www.earth.com/news/climate-change-will-have-a-global-impact-on-agriculture/">agriculture</a>, including rainfed cereal production and animal grazing.&nbsp;



ESA reports that the country’s agricultural system faces a growing number of issues, with climate-related vulnerabilities such as drought, floods and extreme temperatures occurring more frequently. 



Diamonds are amongst the minerals found in the mountains. Indeed, Lesotho can truly be called the Kingdom in the Sky. Beautiful, culturally rich, safe, affordable, and easily accessible from Durban and Johannesburg, mountainous Lesotho is a vastly underrated travel destination. the Kingdom of Lesotho (Sotho: 'Muso oa Lesotho) is an enclaved country in southern Africa. It is just over 30,000 km2 (11,583 sq mi) in size and has a population of around 2 million.



Video Credit: ESA&nbsp;&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer 



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Lesotho: Africa's "Kingdom in the Sky"

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Today's Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features Dublin, the capital and largest city of Ireland. Beyond its pub culture, Dublin is known as a modern culinary destination and a UNESCO City of Literature.



"Dublin is located near the midpoint of Ireland’s east coast in the province of Leinster. The city, which covers an area of around 115 square kilometers, is bordered by the Dublin Mountains, a low mountain range to the south, and is surrounded by flat farmland to the north and west," says ESA.



"The city straddles the River Liffey, which rises in the Wicklow Mountains and flows around 80 kilometers eastwards through the city of Dublin, in which it is canalised and bordered with quays. It then empties into Dublin Bay, an arm of the Irish Sea."



Dublin has an abundance of green spaces, including one of the largest enclosed public parks in any European capital city. Phoenix Park, which was originally formed as a royal hunting park in the 1660s, includes 707 hectares of green space.



Video Credit: ESA&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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The city of Dublin on Ireland's east coast

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Today's Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features the province of Zaragoza in northeast Spain. The image was captured by the Copernicus Sentinel-2 mission.



"Together with the provinces of Huesca and Teruel, Zaragoza formed the old kingdom of Aragon. Its capital, also called Zaragoza (not visible in this image) is home to around half of Aragon’s population," says ESA.



"The Ebro River can be seen winding its way through the province from west to east in this image. Between its source in the Cantabrian Mountains in the northwest and its delta on the Mediterranean coast, the Ebro River is fed by more than 200 tributaries as it flows 910 km across much of northern Spain."



Since rainfall is very scarce in this region, irrigation in the Ebro basin is critically important. In the valleys surrounding the Ebro River, many fields are used for growing crops such as corn, wheat, and barley.



Video/ Image Credit: ESA



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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The province of Zaragoza in northeast Spain

[sendtonews key="oL4FnPTGCV-2384527-12187" type="single"] Today's Video of the Day from the...

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Today’s Video of the Day from <a href="https://earthobservatory.nasa.gov/">NASA Earth Observatory</a> reveals the evolution of the Columbia Glacier in southeastern Alaska. Columbia is among the fastest shrinking glaciers in the world, and the video documents its rapid retreat over the years.&nbsp;



Columbia Glacier is a large, multi-branched calving glacier that flows out of the Chugach Mountains to the Prince William Sound.&nbsp;



According to USGS, Columbia had a long history of stability prior to 1980, with a length 41 miles, and small, short-lived advances or retreats.



In the years since 1980, however, satellite images have captured Columbia’s alarming retreat. By using false-color images, scientists can distinguish between snow and ice, open water, vegetation, and rocky debris on the glacier’s surface.



The series of false-color images featured in today's video were acquired over the span of 35 years. You can see that by 2021, the glacier’s main branch had retreated about 15 miles from its initial position.



The Columbia Glacier has also lost more than 50 percent of its volume, mostly due to calving. <a href="https://www.earth.com/video/nasa-reveals-3d-visual-of-an-atmospheric-river/">NASA</a> reports that while climate change likely started the retreat, mechanical processes kept the disintegration going.



The NASA images are provided by Jesse Allen, Robert Simmon, Joshua Stevens, and Lauren Dauphin using data from Landsat satellites, from the U.S. Geological Survey, and data from MODIS on NASA’s Terra satellite. The structure of Columbia’s moraine played a large role in the stability of the glacier before 1980. 



Like other tidewater glaciers, the Columbia built up a moraine over time, and the mixture of ice and rock functioned like a dam keeping out the sea. It was supported on one end by the shoreline and by the underwater terminal moraine at the other.



Video Credit: NASA Earth Observatory/&nbsp; NASA’s Scientific Visualization Studio



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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The rapid retreat of the Columbia Glacier

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> features the Pyrenees Mountains, which form a natural boundary between France and Spain in southwest Europe.



The mountain range is 430 kilometers in length. It stretches from the Mediterranean Sea on the east to the Atlantic Ocean on the west.



At an elevation of 3404 meters, Pico de Aneto is the highest mountain peak in the Pyrenees, and the third-highest peak in Spain. Pico de Aneto is located in the Posets-Maladeta Natural Park, which spans more than 82,000 acres.&nbsp;



"Geological studies have revealed that the Pyrenees Mountains have been around for longer than the Alps, with their sediments first deposited in coastal basins during the Paleozoic and Mesozoic eras," reports ESA.



"The entire mountain range formed due to the upwelling of large sedimentary rocks by the collision of the Iberian and the Eurasian plate around 100 to 150 million years ago, followed by intense erosion from ice and water."



The western Pyrenees receive more precipitation due to moisture blowing in from the Atlantic Ocean. The mountain range contains many lakes, several small glaciers, and some of the highest waterfalls in Europe.



Video &amp; Image Credit: ESA



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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The Pyrenees Mountains in southwest Europe

[sendtonews key="6HyfrAJTBI-1831843-12187" type="single"] Today’s Video of the Day from the...

Earth,Like,Exoplanet,3d,Render

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Today's Video of the Day from <a href="https://www.nasa.gov/goddard">NASA Goddard</a> describes two exoplanets that are orbiting a star 218 light-years away. A team of researchers led by the University of Montreal has found evidence that these planets are "water worlds."



The experts used data from NASA’s Hubble and Spitzer Space Telescopes. They discovered that exoplanets Kepler-138 c and Kepler-138 could be composed largely of water.



"We previously thought that planets that were a bit larger than Earth were big balls of metal and rock, like scaled-up versions of Earth, and that's why we called them super-Earths," explained study co-author Björn Benneke.&nbsp;



"However, we have now shown that these two planets, Kepler-138 c and d, are quite different in nature and that a big fraction of their entire volume is likely composed of water. It is the best evidence yet for water worlds, a type of planet that was theorized by astronomers to exist for a long time."



Video Credit: NASA Goddard



Image Credit: NASA, ESA, and Leah Hustak (STScI)



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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Two distant planets may be "water worlds"

[sendtonews key="QIoVYJqRBi-2434608-12187" type="single"] Today's Video of the Day from NASA...

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Satellites reveal how Earth's systems are interconnected Today’s Video of the Day from <a href="https://www.nasa.gov/goddard">NASA Goddard</a> describes Earth’s interconnected systems, and how this network is affected by rising temperatures.&nbsp;



During 2020, average global temperatures matched the hottest year on record. The hurricane season was also record-breaking, with many of the storms intensifying at extraordinary speeds. Hot water in the ocean is fuel for hurricanes. The satellite data shows that it's all one interconnected system showing how Satellites reveal how Earth's systems are interconnected.



According to NASA, dust swept up from Northern Africa plays a major role in the formation of hurricanes, and is also a key source of fertilization in the Amazon rainforest. As a result of<a href="https://www.earth.com/news/seagrass-wasting-disease-is-fueled-by-climate-change/"> climate</a> change, dust plumes are expected to decline, which will have an effect on vegetation far away.&nbsp;



Images from Earth-observing satellites show how the world’s plant life is affected by natural disasters, fires, and deforestation. Satellites also reveal how widespread changes in vegetation impact waterways,&nbsp; the climate, air quality. Satellites communicate by using radio waves to send signals to the antennas on the Earth. "Earth From Space" is a groundbreaking two-hour special that reveals a spectacular new space-based vision of our planet. 



Video Credit: NASA Goddard&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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Satellites reveal how Earth's systems are interconnected

[sendtonews key="JbW4VsY53O-1632195-12187" type="single"] Satellites reveal how Earth's systems are interconnected...

Today’s Video of the Day from the <a href="https://welcome.miami.edu/">University of Miami</a> Rosenstiel School of Marine and Atmospheric Science explores how changes in water temperatures have affected tiger shark habitats and movements in the North Atlantic Ocean. The study reveals that rising temperatures have caused the sharks to shift toward the poles over the past 40 years.



“Tiger shark annual migrations have expanded poleward, paralleling rising water temperatures,” explained study lead author Neil Hammerschlag. “These results have consequences for tiger shark conservation, since shifts in their movements outside of marine protected areas may leave them more vulnerable to commercial fishing.”



The researchers analyzed nine years of tracking data from satellite-tagged tiger sharks, combined with four decades of conventional tag and recapture data provided by National Oceanic and Atmospheric Administration (NOAA) Cooperative Shark Tagging Program.



The experts found that during the last decade of record heat, for every one-degree Celsius increase in water temperatures, tiger sharks migrated further poleward by over 400 kilometers. They also migrated two weeks earlier than usual to waters off the northeastern coast of the United States.



“Given their role as apex predators, these changes to tiger shark movements may alter predator-prey interactions, leading to ecological imbalances, and more frequent encounters with humans,” concluded Professor Hammerschlag.



Video Credit: University of Miami Rosenstiel School of Marine and Atmospheric Science



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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Tiger sharks are shifting poleward as temperatures rise

Today’s Video of the Day from the University of Miami...

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> is focused on the melt ponds that emerge during the spring and summer on the Greenland Ice Sheet, which is the largest ice mass in the northern hemisphere.



"Melt ponds are vast pools of open water that form on both sea ice and ice sheets and are visible as turquoise-blue pools of water in this Copernicus Sentinel-2 image," says ESA.



"When snow and ice melts atop glaciers, water flows in channels and streams and collects in depressions on the surface. These melt ponds can speed up the melting of the surrounding ice since they greatly reduce the ice’s ability to reflect sunlight."



"This can create a positive feedback where an increasing number of melt ponds absorb more heat which causes ice cover to melt even faster."



According to ESA, Greenland has been hit with a late-season heatwave that began in early September. This caused the type of melt event that usually occurs in the middle of summer.



"In a recent paper published in Nature Climate Change, scientists found that major sea-level rise from the melting of the Greenland ice cap is now ‘inevitable’ even if the burning of fossil fuels were to halt overnight," says ESA. "Using satellite observations of Greenland ice loss and ice cap from 2000 to 2019, the team found the losses will lead to a minimum rise of 27 cm regardless of climate change."



Video Credit: ESA&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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Melt ponds on the Greenland Ice Sheet

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> describes a new map of Mars that is providing insight into the planet’s watery past. The map also reveals where future missions could safely land on Mars.&nbsp;



The map has been created over the last decade using observations of water-rich rocks and mineral deposits. The images were captured by ESA’s Mars Express and NASA’s Mars Reconnaissance Orbiter.



"A big surprise is the prevalence of these minerals, with the map revealing hundreds of thousands of water-affected locations in the oldest parts of the planet," says ESA. "The new data will help answer exciting questions about Mars’ climate history, whether water was globally persistent or confined to short, intense episodes, and whether the conditions were ever suitable for life."



"Specifically, the map shows the locations and abundances of aqueous minerals. These are from rocks that have been chemically altered by the action of water in the past, and have typically been transformed into clays and salts."



According to John Carter of the Institut d’Astrophysique Spatiale (IAS), our collective understanding of Mars has been oversimplified. He explained that planetary scientists have tended to think that only a few types of clay minerals on Mars were created during its wet period, then as the water gradually dried up, salts were produced across the planet.



The new map shows that the composition of Mars is much more complicated than what we thought. For example, while many salts formed after Martian clays, there are some salts that are presumed to be older than some of the clays.&nbsp;



“The evolution from lots of water to no water is not as clear cut as we thought, the water didn’t just stop overnight. We see a huge diversity of geological contexts, so that no one process or simple timeline can explain the evolution of the mineralogy of Mars. That’s the first result of our study. The second is that if you exclude life processes on Earth, Mars exhibits a diversity of mineralogy in geological settings just as Earth does,” said Carter.



Video Credit: ESA



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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The history of Mars is much more complex than we thought

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Today's Video of the Day from the <a href="https://www.stowers.org/">Stowers Institute for Medical Research</a> describes how cavefish adapted to a sedentary lifestyle over tens of thousands of years. 



The experts found that the muscle metabolism of cavefish has been genetically reprogrammed over time. As a result, the animals have experienced major changes in their morphology and behavior. Despite these changes, however, the cavefish remain healthy and fit.



The research may provide new clues about the evolutionary consequences of prolonged physical inactivity in humans.&nbsp;



“It’s no surprise that people are moving less and less as technology has advanced,” said Rohner. “With cavefish, we have a unique system where we can study what might happen if people remained couch potatoes over very, very long periods of time.”



Video Credit: Stowers Institute for Medical Research



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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Cavefish are healthy despite their sedentary lifestyle

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Today’s Video of the Day from <a href="https://earthobservatory.nasa.gov/">NASA Earth Observatory</a> some of the most incredible waves in the world, as seen by Landsat satellites.



"With more than 370,000 miles of coastline on Earth, there are plenty of places where epic waves build up, curl over, and hurtle toward the shore.- much to the thrill of surfers," says NASA. "There are some places where these waves are so magnificent that they can be seen from space."



"With the broad perspective of satellites, we can see how these iconic waves develop into the world’s tallest, longest, fastest, and heaviest."



Video Credit: NASA Earth Observatory&nbsp;



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By <a href="mailto:csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Editor



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Satellites capture the world's biggest and fastest waves

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Today’s Video of the Day from the <a href="https://www.esa.int/">European Space Agency</a> describes why satellite images and measurements of our planet have become "essential to our survival, offering a new outlook of our world."&nbsp;



Rising sea levels pose one of the biggest societal threats associated with climate change. According to ESA, satellite altimeter missions such as Copernicus Sentinel-6 are essential in monitoring global and regional changes in sea level.



"Unbeknown to many, the island of Crete, Greece, plays an important role in the Copernicus satellite altimetry constellation and on an international stage," reports ESA.



"Satellite altimetry data have to be continuously monitored at the ESA’s Permanent Facility for Altimetry Calibration where different techniques have pioneered the use of transponders to provide the best measurements to validate satellite altimeters in space soon after launch."



Dr. Craig Donlon explains that, by understanding planet Earth through satellite measurements, we are able to find evidence of change.&nbsp;



Video Credit: European Space Agency&nbsp;



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By <a href="http://csexton@earth.com">Chrissy Sexton</a>, <a href="https://www.earth.com/staff/">Earth.com</a> Staff Writer

Satellites have become essential to our survival

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